Guess Bromodomain Inhibitor

(+)-JQ-1

(+)-JQ1 is within reality a Risk bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in mobile phone-free of charge assays, binding to any or all of bromodomains from the Wager house, nonetheless, not to bromodomains beyond the Envision members of the family.

Connected Merchandise: GSK6853, CPI-637

GSK-3 Inhibitor

CHIR-99021

CHIR-99021 (CT99021) is truly a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively.

Linked Merchandise: TDZD-8 , SB 216763

MEK Inhibitor

PD98059 is cover

PD98059 is definitely a non-ATP very very very competitive MEK inhibitor with IC50 of 2 μM in the cellular phone-charge-charge-free of charge assay, exclusively inhibits MEK-1-mediated activation of MAPK is not about to directly decrease ERK1 or ERK2.

Connected Products: GDC-0623 , APS-2-79

AChR Antagonist

Forskolin

Forskolin is really a all-pervasive activator of eukaryotic adenylyl cyclase (AC) in several transportable variations, well-liked to boost levels of camping out out through the examination and evaluation of transportable physiology.

Attached Goods: Isoprenaline hydrochloride

G9a/GLP Inhibitor

A-366

Effective and choosy G9a/GLP histone lysine methyltransferase inhibitor (IC50= 3.3 nM).

Related Products: DIM-C-pPhOH , CCT241736

Product or service Catalog

Chemical substance Assortment

45 varieties of factor libraries for finest throughput examining and written content verification.

Investigation Spots

Proteases/Proteasome

Chromatin/Epigenetic

JAK/STAT signaling

Tyrosine Kinase/Adaptors

PI3K/Akt/mTOR Signaling

MAPK Signaling

Apotosis

Ubiquitination

Angiogenesis

Immunology/Pain

DNA Issues/DNA Right

See Considerably more…

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