Homology-reliant DNA Repair Inhibitor
YU238259 is actually a innovative inhibitor of homology-based DNA restoration(HDR), but fails to slow down non-homologous conclusion-becoming a member of (NHEJ), in mobile phone-centered GFP reporter assays.
Associated Items:Bucladesine salt salt
PF-04929113 Mesylate, a prodrug of SNX-2112, is definitely an orally productive Hsp90 inhibitor, by using a Kd of 41 nM, plus triggers Her-2 deterioration, by having an IC50 of 37 nM.
Related Goods: Resminostat hydrochloridel
Histone methyltransferase Inhibitor
A-196 is really a potent and discerning inhibitor of SUV420H1 and SUV420H2 with IC50 values of .025 and .144 μM, respectively more than 100-fold selective over other histone methyltransferases and non-epigenetic concentrates on..
Connected Products: Ac-CoA Synthase Inhibitor1
Ephrin Receptor inhibitor
ALW-II-41-27 is really a novel Eph receptor tyrosine kinase inhibitor, useful for many forms of cancer therapy.
Related Goods: Pimodivir , MS049
Tyrosine Kinases inhibitor
Sitravatinib (MGCD516) can be a innovative little molecule inhibitor concentrating on several RTKs involved with driving a vehicle sarcoma mobile phone expansion, which include c-Set, PDGFRβ, PDGFRα, c-Satisfied, and Axl.
Relevant Products: Miriplatin ,RAD140
45 varieties of substance libraries for high throughput testing and high content verification.
DNA Problems/DNA Maintenance
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