Popular Materials in Protease Inhibitor Assortment

proteasome

MG-132  CAS No. 133407-82-6

MG-132 is definitely an inhibitor of proteasome with IC50 of 100 nM in the mobile phone-free of cost assay, plus inhibits calpain with IC50 of 1.2 μM.

20S proteasome

Bortezomib  CAS No. 179324-69-7

Bortezomib  (PS-341) might be a powerful 20S proteasome inhibitor with Ki of .6 nM from the mobile phone-cost-free assay.

proteasome

Carfilzomib  CAS No. 868540-17-4

Carfilzomib (PR-171) is certainly an permanent proteasome inhibitor with IC50 of <5 nM in ANBL-6 mobile fabric, showcased preferential in vitro inhibitory performance facing the ChT-L action inside the β5 subunit, but virtually no effect on the PGPH and T-L workouts.

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