PAC-1 CAS No. 315183-21-2
PAC-1 is actually a powerful procaspase-3 activator with EC50 of .22 μM as well as the initial small molecule viewed to directly activate procaspase-3 to caspase-3.
Pifithrin-α CAS No. 63208-82-2
Pifithrin-α is definitely an inhibitor of p53, suppressing p53-centered transactivation of p53-receptive genes.
A-1210477 CAS No. 1668553-26-1
A-1210477 is really a strong and discerning MCL-1 and Bcl-2 inhibitor with Ki and IC50 of .454 nM and 26.2 nM, respectively,Andgt100-fold selectivity over other Bcl-2 members of your family.
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