Popular Inhibitors

IDO inhibitor

VX-11e Chemical substance Composition NLG919

NLG919 is actually a effective IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with KiEC50 of 7 nM75 nM in cellular-totally free assays. Period 1.

Related Merchandise Indoximod, INCB024360 analogue

TNF-α inhibitor

Trovirdine (LY-300046) Chemical Composition CPI-1189

CPI-1189 (REN-1189) is a TNF-α release inhibitor potentially for dealing with sciatica and postherpetic neuralgia.

Associated Merchandise CX691 , Compound 4

Antiepileptic Medicine

DB07268 Compound Composition Valrocemide

Valrocemide(Television set-1901), is undoubtedly an antiepileptic medicine (AED). Valrocemide

 includes a wide range of anticonvulsant action and guaranteeing prospective as being a new AED.

Connected Goods Lvguidingan , NS 638

VEGFR Inhibitor

BML-210 Chemical Composition SU 5205

SU 5205 is a VEGFR2 inhibitor.

Related Goods PF-CBP1 , SR-3029

PDGFR Inhibitor

AMG-337 Substance Framework NSC 86429

NSC 86429, also referred to as DMBI, is a strong and picky inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 ideals are .8 and 19.4 μM respectively). SU4312 unexpectedly protects against MPP(+) -caused neurotoxicity via particular and immediate inhibition of neuronal NOS.

Related Items I-CBP112 , CK-1752

IKr Station Blocker

JNJ-42165279 Substance Framework CK-1752

Sematilide, often known as CK-1752, is really a school III antiarrhythmic. This is a discerning delayed rectifier K+ current (IKr) funnel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of action prospective timeframe and refractoriness.

Associated Goods XL-652 , WAY 200070

Merchandise Catalog

Substance Collection

45 varieties of substance libraries for top throughput evaluating and high content testing.

Research Areas

ProteasesProteasome

ChromatinEpigenetic

JAKSTAT signaling

Tyrosine KinaseAdaptors

PI3KAktmTOR Signaling

MAPK Signaling

Apotosis

Ubiquitination

Angiogenesis

ImmunologyInflammation

DNA DamageDNA Maintenance

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