Popular Inhibitors

IDO inhibitor

VX-11e Chemical substance Composition NLG919

NLG919 is actually a effective IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with KiEC50 of 7 nM75 nM in cellular-totally free assays. Period 1.

Related Merchandise Indoximod, INCB024360 analogue

TNF-α inhibitor

Trovirdine (LY-300046) Chemical Composition CPI-1189

CPI-1189 (REN-1189) is a TNF-α release inhibitor potentially for dealing with sciatica and postherpetic neuralgia.

Associated Merchandise CX691 , Compound 4

Antiepileptic Medicine

DB07268 Compound Composition Valrocemide

Valrocemide(Television set-1901), is undoubtedly an antiepileptic medicine (AED). Valrocemide

 includes a wide range of anticonvulsant action and guaranteeing prospective as being a new AED.

Connected Goods Lvguidingan , NS 638

VEGFR Inhibitor

BML-210 Chemical Composition SU 5205

SU 5205 is a VEGFR2 inhibitor.

Related Goods PF-CBP1 , SR-3029

PDGFR Inhibitor

AMG-337 Substance Framework NSC 86429

NSC 86429, also referred to as DMBI, is a strong and picky inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 ideals are .8 and 19.4 μM respectively). SU4312 unexpectedly protects against MPP(+) -caused neurotoxicity via particular and immediate inhibition of neuronal NOS.

Related Items I-CBP112 , CK-1752

IKr Station Blocker

JNJ-42165279 Substance Framework CK-1752

Sematilide, often known as CK-1752, is really a school III antiarrhythmic. This is a discerning delayed rectifier K+ current (IKr) funnel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of action prospective timeframe and refractoriness.

Associated Goods XL-652 , WAY 200070

Merchandise Catalog

Substance Collection

45 varieties of substance libraries for top throughput evaluating and high content testing.

Research Areas



JAKSTAT signaling

Tyrosine KinaseAdaptors

PI3KAktmTOR Signaling

MAPK Signaling





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