IDO inhibitor
VX-11e Chemical substance Composition NLG919
NLG919 is actually a effective IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with KiEC50 of 7 nM75 nM in cellular-totally free assays. Period 1.
Related Merchandise Indoximod, INCB024360 analogue
TNF-α inhibitor
Trovirdine (LY-300046) Chemical Composition CPI-1189
CPI-1189 (REN-1189) is a TNF-α release inhibitor potentially for dealing with sciatica and postherpetic neuralgia.
Associated Merchandise CX691 , Compound 4
Antiepileptic Medicine
DB07268 Compound Composition Valrocemide
Valrocemide(Television set-1901), is undoubtedly an antiepileptic medicine (AED). Valrocemide
includes a wide range of anticonvulsant action and guaranteeing prospective as being a new AED.
Connected Goods Lvguidingan , NS 638
VEGFR Inhibitor
BML-210 Chemical Composition SU 5205
SU 5205 is a VEGFR2 inhibitor.
Related Goods PF-CBP1 , SR-3029
PDGFR Inhibitor
AMG-337 Substance Framework NSC 86429
NSC 86429, also referred to as DMBI, is a strong and picky inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 ideals are .8 and 19.4 μM respectively). SU4312 unexpectedly protects against MPP(+) -caused neurotoxicity via particular and immediate inhibition of neuronal NOS.
Related Items I-CBP112 , CK-1752
IKr Station Blocker
JNJ-42165279 Substance Framework CK-1752
Sematilide, often known as CK-1752, is really a school III antiarrhythmic. This is a discerning delayed rectifier K+ current (IKr) funnel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of action prospective timeframe and refractoriness.
Associated Goods XL-652 , WAY 200070
Merchandise Catalog
Substance Collection
45 varieties of substance libraries for top throughput evaluating and high content testing.
Research Areas
ProteasesProteasome
ChromatinEpigenetic
JAKSTAT signaling
Tyrosine KinaseAdaptors
PI3KAktmTOR Signaling
MAPK Signaling
Apotosis
Ubiquitination
Angiogenesis
ImmunologyInflammation
DNA DamageDNA Maintenance
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