Materials in Protease Inhibitor Local library

Materials in Protease Inhibitor Local library

proteasome

MG-132 CAS No. 133407-82-6

MG-132 is definitely an inhibitor of proteasome with IC50 of 100 nM in the cell-cost-free assay, plus inhibits calpain with IC50 of 1.2 μM.

20S proteasome

Bortezomib CAS No. 179324-69-7

Bortezomib (PS-341) is really a strong 20S proteasome inhibitor with Ki of .6 nM in the cell-free of charge assay.

proteasome

Carfilzomib CAS No. 868540-17-4

Carfilzomib (PR-171) is undoubtedly an irrevocable proteasome inhibitor with IC50 of <5 nM in ANBL-6 tissues, displayed preferential in vitro inhibitory potency versus the ChT-L process from the β5 subunit, but little or no result on the PGPH and T-L routines.

Leave a Reply

Your email address will not be published. Required fields are marked *